Respiratory syncytial virus therapies — Flashcards

Flashcard 1: Which HAART drugs prevent mature virion formation from large polypeptides?_____

Answer: Protease inhibitors

Flashcard 2: Oseltamavir / zanamavir also prevent influenza by impairing viral penetration of _____ that overlie the respiratory epithelium

Answer: mucous secretions

Flashcard 3: Palivizumab is a monoclonal antibody against the _____ of RSV

Answer: fusion (F) protein

Flashcard 4: Ribavirin is a _____ analog

Answer: guanosine nucleoside

Flashcard 5: Which type of HAART drug is Ritonavir?_____

Answer: Protease inhibitor

Flashcard 6: NS3/NS4A protease inhibitors and NS5A inhibitors are under clinical investigation to develop HCV treatment regimens that do not require _____ administration

Answer: interferon/ribavirin

Flashcard 7: A major side effect of ribavirin is that it may cause _____

Answer: dose-dependent hemolytic anemia (10-20% of patients)

Flashcard 8: amantadine

Answer:

Extra: Parkinson's disease, influenza A, rubellaexact mechanism unclear, but leads to increased dopamine releaseataxia

Flashcard 9: NRTIs and _____ both are reverse transcriptase inhibitors used in the treatment of HIV

Answer: NNRTIs

Extra:    https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki 

Flashcard 10: Enfuvirtide binds _____ of HIV inhibiting viral cell fusion with host cells

Answer: gp41

Extra:   Watch Maraviroc, fusion inhibitors, integrase inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-maraviroc-fusion-inhibitors-integrase-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki