HIV protease inhibitors — Flashcards

Flashcard 1: Which HAART drugs prevent mature virion formation from large polypeptides?_____

Answer: Protease inhibitors

Flashcard 2: Protease inhibitors can cause hyperlipidemia with _____ (increased central adiposity)

Answer: lipodystrophy

Flashcard 3: Which type of HAART drug is Atazanavir?_____

Answer: Protease inhibitor

Flashcard 4: NNRTIs have varying effects on _____ and thus may have many drug interactions

Answer: CYP450

Flashcard 5: Which type of HAART drug is Indinavir?_____

Answer: Protease inhibitor

Flashcard 6: Which type of HAART drug is Ritonavir?_____

Answer: Protease inhibitor

Flashcard 7: Which type of HAART drug is Darunavir?_____

Answer: Protease inhibitor

Flashcard 8: amantadine

Answer:

Extra: Parkinson's disease, influenza A, rubellaexact mechanism unclear, but leads to increased dopamine releaseataxia

Flashcard 9: NRTIs and _____ both are reverse transcriptase inhibitors used in the treatment of HIV

Answer: NNRTIs

Extra:    https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki 

Flashcard 10: Enfuvirtide binds _____ of HIV inhibiting viral cell fusion with host cells

Answer: gp41

Extra:   Watch Maraviroc, fusion inhibitors, integrase inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-maraviroc-fusion-inhibitors-integrase-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki