HIV entry inhibitors US Medical PG Flashcards - Medical Study Cards
Master HIV entry inhibitors with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
HIV entry inhibitors Flashcard Deck - 10 Cards
Flashcard 1: Resistance to Cidofovir and Foscarnet occurs with mutations to _____
Answer: viral DNA polymerase
Flashcard 2: Highly active antiretroviral therapy (HAART) consists of a minimum of _____ drugs to prevent resistance
Answer: 3
Flashcard 3: Which HAART drug binds to gp41?_____
Answer: Enfuvirtide
Flashcard 4: HIV protease inhibitors _____ cytochrome P-450
Answer: inhibit
Flashcard 5: amantadine
Answer:
Extra: Parkinson's disease, influenza A, rubella exact mechanism unclear, but leads to increased dopamine release ataxia
Flashcard 6: _____ insert themselves into the DNA of the reverse transcriptase, halting further elongation
Answer: NRTIs
Extra:
https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki
Flashcard 7: Enfuvirtide binds _____ of HIV inhibiting viral cell fusion with host cells
Answer: gp41
Extra:
Watch Maraviroc, fusion inhibitors, integrase inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-maraviroc-fusion-inhibitors-integrase-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 8: NRTIs and _____ both are reverse transcriptase inhibitors used in the treatment of HIV
Answer: NNRTIs
Extra:
https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki
Flashcard 9: Ganciclovir triphosphate then incorporates into viral DNA, inhibiting _____
Answer: viral DNA-dependent DNA polymerase
Extra:
Watch Ganciclovir, valganciclovir, foscarnet, cidofovir [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-other-ganciclovir-valganciclovir-foscarnet-cidofovir?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 10: Patients taking acyclovir, famciclovir, valacyclovir are at risk of obstructive crystalline nephropathy and acute renal failure if not adequately _____
Answer: hydrated
Extra:
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
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