Cytomegalovirus antivirals US Medical PG Flashcards - Medical Study Cards
Master Cytomegalovirus antivirals with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Cytomegalovirus antivirals Flashcard Deck - 10 Cards
Flashcard 1: Ganciclovir and Valganciclovir are used as prophylaxis of CMV retinitis in the _____
Answer: immunocompromised
Flashcard 2: What is the mechanism of resistance to Acyclovir/Famciclovir/Valacyclovir?_____
Answer: Mutated/Absent Thymidine Kinase
Flashcard 3: Treatment for CMV includes _____, Valganciclovir or Foscarnet/cidofovir
Answer: Ganciclovir
Flashcard 4: Cidofovir (a CMV retinitis drug) is administered with probenecid and IV saline to _____
Answer: reduce nephrotoxicity
Flashcard 5: Resistance in CMV to ganciclovir occurs with mutations in the _____ gene
Answer: UL97
Flashcard 6: amantadine
Answer:
Extra: Parkinson's disease, influenza A, rubella exact mechanism unclear, but leads to increased dopamine release ataxia
Flashcard 7: _____ insert themselves into the DNA of the reverse transcriptase, halting further elongation
Answer: NRTIs
Extra:
https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki
Flashcard 8: Enfuvirtide binds _____ of HIV inhibiting viral cell fusion with host cells
Answer: gp41
Extra:
Watch Maraviroc, fusion inhibitors, integrase inhibitors [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-hiv-maraviroc-fusion-inhibitors-integrase-inhibitors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 9: NRTIs and _____ both are reverse transcriptase inhibitors used in the treatment of HIV
Answer: NNRTIs
Extra:
https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki
Flashcard 10: Ganciclovir triphosphate then incorporates into viral DNA, inhibiting _____
Answer: viral DNA-dependent DNA polymerase
Extra:
Watch Ganciclovir, valganciclovir, foscarnet, cidofovir [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-antivirals-other-ganciclovir-valganciclovir-foscarnet-cidofovir?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
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