Sulfonamides and trimethoprim US Medical PG Flashcards - Medical Study Cards
Master Sulfonamides and trimethoprim with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Sulfonamides and trimethoprim Flashcard Deck - 10 Cards
Flashcard 1: Trimethoprim inhibits the enzyme _____
Answer: Dihydrofolate Reductase
Flashcard 2: Which enzyme is inhibited by trimethoprim (TMP)?_____
Answer: Dihydrofolate reductase (prokaryotic)
Flashcard 3: What nephrotoxicity is caused by Sulfonamides?_____
Answer: Acute interstitial nephritis
Flashcard 4: _____ can be used in prophylaxis and treatment of pneumocystis pneumonia in patients without sulfa drug allergies
Answer: Trimethoprim/Sulfamethoxazole (TMP-SMX)
Flashcard 5: Which antibiotics are used for prophylaxis and treatment of Pneumocystis jirovecii pneumonia?_____
Answer: Trimethoprim-Sulfamethoxazole (TMP-SMX)
Flashcard 6: Sulfonylureas are _____ drugs and thus may cause adverse reactions in allergic patients
Answer: sulfa
Flashcard 7: Sulfonamides are _____ of CYP-450
Answer: inhibitors
Flashcard 8: _____-toxicity is associated with Isoniazid use
Answer: Hepato
Extra:
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Flashcard 9: Clavulanic acid (clavulanate) is a suicide β-lactamase inhibitor that is combined with the aminopenicillin _____ (Augmentin) or the antipseudomonal _____
Answer: amoxicillin
Extra:
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https://onlinemeded.org/spa/infectious-disease?ref=anki
Flashcard 10: β-lactam antibiotics inhibit what family of enzymes involved in cell wall synthesis?
_____
Answer: Penicillin binding protein transpeptidases
Extra:
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https://onlinemeded.org/spa/infectious-disease?ref=anki
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