Macrolides, ketolides, and lincosamides — Flashcards

Macrolides, ketolides, and lincosamides — Flashcards

Macrolides, ketolides, and lincosamides — Flashcards
#1

Macrolides are _____ of CYP-450

#2

Which antibiotic is used as treatment of oral infections and aspiration pneumonia caused by Bacteroides fragilis?_____

#3

Macrolides (-thromycin) can prolong the _____, predisposing to Torsades de pointes

#4

Which two antibiotics bind to the 50S subunit of ribosomes and inhibit translocation?_____

#5

Which macrolide antibiotic(s) inhibit CYP450?_____

#6

Which antibiotic binds the 30S ribosomal subunit, irreversibly inhibiting formation of the initiation complex?_____

#7

Clavulanic acid (clavulanate) is a suicide β-lactamase inhibitor that is combined with the aminopenicillin _____ (Augmentin) or the antipseudomonal _____

#8

β-lactam antibiotics inhibit what family of enzymes involved in cell wall synthesis? _____

#9

_____-toxicity is associated with Isoniazid use

#10

Cephalosporins can cause a Vitamin _____ deficiency

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