Neurodegenerative diseases US Medical PG Flashcards - Medical Study Cards
Master Neurodegenerative diseases with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Neurodegenerative diseases Flashcard Deck - 10 Cards
Flashcard 1: The number of neurofibrillary tangles in Alzheimer's correlates with degree of _____
Answer: dementia
Flashcard 2: _____ dementia is a result of multiple arterial infarcts and/or chronic ischemia (e.g. hypertension, atherosclerosis, vasculitis)
Answer: Vascular
Flashcard 3: Frontotemporal dementia (Pick disease) may have ubiquitinated _____ inclusions seen on histology
Answer: TDP-43
Flashcard 4: Lewy body dementia is characterized by intracellular lewy bodies primarily in the _____
Answer: cortex (location in the brain)
Flashcard 5: What pathology is characterized by degeneration of the basal nucleus of Meynert? _____
Answer: Alzheimer disease
Flashcard 6: What is the term for infarcted tissue in the basal ganglia or internal capsule caused by occlusion of a lenticulostriate artery?
Answer: lacunar infarct
Flashcard 7: epidural hematoma
Answer: rupture of middle meningeal artery; fracture of temporal bone
Extra: rapid arterial bleeding lucid interval followed by decreased LOC; CN 3 palsy, increased ICP CT: biconvex, hyperdense blood; does not cross sutures; may cross falx, tentorium
Flashcard 8: central pontine myelinolysis
Answer: often iatrogenic; caused by rapid correction of hyponatremia
Extra: massive axonal demyelination of pontine white matter tracts acute paralysis, dysarthria, dysphagia, diplopia, loss of consciousness; +/- locked-in syndrome T2 MRI: increased signal in central pons
Flashcard 9: subdural hematoma
Answer:
Extra: slow venous bleeding via rupture of bridging veins decreased LOC, increased ICP CT: crescent shaped, hyperdense blood; midline shift; may cross sutures; does not cross falx, tentorium
brain atrophy elderly, alcoholics
Flashcard 10: subarachnoid hemorrhage
Answer:
Extra: rapid arterial bleeding after rupture of aneurysm "worst headache of my life", decreased LOC, increased ICP bloody or yellow CSF CT: blood conforms to shape of gyri, pools in cisterns
nimodipine for late-onset vasospasm vasospasm 2-3 days later, potential for rebleed
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