Mutations in which tumor suppressor gene can lead to von Hippel-Lindau disease?_____
#2
Mutations in which tumor suppressor genes can lead to Wilms Tumors?_____
#3
Li-Fraumeni syndrome is characterized by multiple malignancies at an _____ age
#4
Mutations in which tumor suppressor gene can lead to Melanoma, Pancreatic Cancer, and Dysplastic Nevus Syndrome?_____
#5
Loss of p53 is seen in >_____% of cancers
#6
Which tumor suppressor gene is associated with von Hippel-Lindau disease?_____
#7
What inherited cancers (2) are associated with osteosarcoma? _____
#8
Which tumor suppressor gene is associated with melanoma and pancreatic cancer?_____
#9
A _____ of function mutation to a tumor suppressor gene increases the risk of cancer
#10
Which tumor suppressor genes are associated with Wilms tumor (nephroblastoma)?_____
Tumor suppressor genes US Medical PG Flashcards - Medical Study Cards
Master Tumor suppressor genes with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Tumor suppressor genes Flashcard Deck - 10 Cards
Flashcard 1: Mutations in which tumor suppressor gene can lead to von Hippel-Lindau disease?_____
Answer: VHL
Flashcard 2: Mutations in which tumor suppressor genes can lead to Wilms Tumors?_____
Answer: WT1 and CDKN1C (WT2)
Flashcard 3: Li-Fraumeni syndrome is characterized by multiple malignancies at an _____ age
Answer: early
Flashcard 4: Mutations in which tumor suppressor gene can lead to Melanoma, Pancreatic Cancer, and Dysplastic Nevus Syndrome?_____
Answer: CDKN2A (not p53)
Flashcard 5: Loss of p53 is seen in >_____% of cancers
Answer: 50
Flashcard 6: Which tumor suppressor gene is associated with von Hippel-Lindau disease?_____
Answer: VHL
Flashcard 7: What inherited cancers (2) are associated with osteosarcoma? _____
Answer: Li-Fraumeni syndrome and familial retinoblastoma
Flashcard 8: Which tumor suppressor gene is associated with melanoma and pancreatic cancer?_____
Answer: CDKN2A
Flashcard 9: A _____ of function mutation to a tumor suppressor gene increases the risk of cancer
Answer: loss
Flashcard 10: Which tumor suppressor genes are associated with Wilms tumor (nephroblastoma)?_____
