If a patient inherits or develops a mutation in a _____ gene, the complementary allele must be deleted/mutated before cancer develops
#2
Myelodysplastic syndromes are caused by _____ or environmental exposure (e.g. radiation, benzene, chemotherapy)
#3
Which tumor suppressor genes are associated with breast, ovarian, fallopian and pancreatic cancer?_____
#4
Mutations in which tumor suppressor genes can lead to Breast, Ovarian, and Pancreatic cancers?_____
#5
Telomerase activity is _____ in cancer
#6
Abnormal expression of miRNAs contributes to certain _____ (e.g. by silencing an mRNA from a tumor suppressor gene)
#7
There is an increased incidence of medullary carcinoma of the breast (a subtype of invasive ductal carcinoma) in patients with _____ mutations
#8
fibroma
#9
Brenner tumor
#10
mucinous cystadenocarcinoma
Epigenetic mechanisms in cancer US Medical PG Flashcards - Medical Study Cards
Master Epigenetic mechanisms in cancer with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Epigenetic mechanisms in cancer Flashcard Deck - 10 Cards
Flashcard 1: If a patient inherits or develops a mutation in a _____ gene, the complementary allele must be deleted/mutated before cancer develops
Answer: tumor suppressor
Flashcard 2: Myelodysplastic syndromes are caused by _____ or environmental exposure (e.g. radiation, benzene, chemotherapy)
Answer: de novo mutations (genetics)
Flashcard 3: Which tumor suppressor genes are associated with breast, ovarian, fallopian and pancreatic cancer?_____
Answer: BRCA1/BRCA2
Flashcard 4: Mutations in which tumor suppressor genes can lead to Breast, Ovarian, and Pancreatic cancers?_____
Answer: BRCA1/BRCA2
Flashcard 5: Telomerase activity is _____ in cancer
Answer: upregulated
Flashcard 6: Abnormal expression of miRNAs contributes to certain _____ (e.g. by silencing an mRNA from a tumor suppressor gene)
Answer: malignancies
Flashcard 7: There is an increased incidence of medullary carcinoma of the breast (a subtype of invasive ductal carcinoma) in patients with _____ mutations
Answer: BRCA1
Flashcard 8: fibroma
Answer:
Extra: pulling sensation in groin bundles of spindle-shaped fiibroblasts
Flashcard 9: Brenner tumor
Answer:
Extra: "coffee bean" nuclei on H&E
Solid tumor, tan-yellow color, appears encapsulated. Looks like bladder benign
Flashcard 10: mucinous cystadenocarcinoma
Answer:
Extra: malignant
Keywords: Epigenetic mechanisms in cancer flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
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