Secondary immunodeficiencies — Flashcards

Flashcard 1: What laboratory technique is useful in determining CD4 cell count in HIV patients? _____

Answer: Flow cytometry

Flashcard 2: HIV-associated dementia can result in activation of _____ cells that form nodules

Answer: microglial

Flashcard 3: Which immunodeficiency is associated with an infiltrative lymphohistiocytosis?_____

Answer: Chediak-Higashi

Flashcard 4: Which subtype of Hodgkin lymphoma is usually seen (strongest association) in the elderly and HIV+ individuals? _____

Answer: Lymphocyte-depleted

Flashcard 5: Which immunodeficiency is caused by failure to repair DNA double strand breaks? _____

Answer: Ataxia-telangiectasia

Flashcard 6: Myeloperoxidase deficiency is associated with increased risk for _____ infection, however, most patients are asymptomatic

Answer: Candida

Flashcard 7: rheumatic fever

Answer: type 3 (?) hypersensitivity (IgM), post S. pyogenes infection

Extra: polyarthritis, endocarditis, subcutaneous nodules, erythema marginatum, Sydenham's chorea