Immune-related adverse events — Flashcards

Flashcard 1: GVHD of the liver presents with similar histologic findings to what immune disorder?_____

Answer: Primary biliary cholangitis

Flashcard 2: Immunodeficiency increases the risk for _____ due to lack of immune surveillence for tumors

Answer: cancer

Flashcard 3: What type of hypersensitivity reaction is Graves disease and Myasthenia Gravis? _____

Answer: Type II HSR (cellular dysfunction)

Flashcard 4: The PD1 receptor is normally involved in the maintainance of _____ immunologic tolerance

Answer: peripheral

Flashcard 5: What is the most common cancer that develops as a result of immunosuppressive therapy? _____

Answer: Squamous cell carcinoma of skin

Flashcard 6: _____ hepatitis is associated with inflammation that involves the lobules of the liver and portal tracts; characterized by apoptosis of hepatocytes

Answer: Acute

Flashcard 7: SCID may be caused by a defective _____ receptor (most common)

Answer: IL-2

Flashcard 8: rheumatic fever

Answer: type 3 (?) hypersensitivity (IgM), post S. pyogenes infection

Extra: polyarthritis, endocarditis, subcutaneous nodules, erythema marginatum, Sydenham's chorea