Plasma cell disorders — Flashcards

Flashcard 1: _____ disorders are neoplastic proliferations of mature cells of myeloid lineage

Answer: Myeloproliferative

Flashcard 2: Hyper-IgM syndrome is characterized by absent _____ on lymph node biopsy

Answer: germinal centers

Flashcard 3: Amyloid may be visualized as _____ under polarized light

Answer: apple-green birefringence

Flashcard 4: Multiple myeloma is associated with _____ of RBCs on blood smear

Answer: Rouleaux formation

Flashcard 5: Multiple myeloma may deposit in tissue, causing _____ amyloidosis

Answer: primary (AL)

Flashcard 6: In multiple myeloma, neoplastic plasma cells produce IL-_____ which stimulates osteoclast activating factor

Answer: 6

Flashcard 7: testicular lymphoma

Answer: mets from primary lymphoma

Extra: poor; aggressiveolder men

Flashcard 8: What kinds of tissue samples can be used for karyotyping?

Answer: blood, bone marrow, amniotic fluid, placental tissue