Myelodysplastic syndromes — Flashcards

Flashcard 1: Myeloproliferative disorders may progress to marrow _____ or transform to acute leukemia

Answer: fibrosis

Flashcard 2: Myelodysplastic syndromes are caused by _____ or environmental exposure (e.g. radiation, benzene, chemotherapy)

Answer: de novo mutations (genetics)

Flashcard 3: What pathologic RBC finding is seen in bone marrow with sideroblastic anemia, lead poisoning, and myelodysplastic syndrome? _____

Answer: Ringed sideroblasts

Flashcard 4: testicular lymphoma

Answer: mets from primary lymphoma

Extra: poor; aggressiveolder men

Flashcard 5: What kinds of tissue samples can be used for karyotyping?

Answer: blood, bone marrow, amniotic fluid, placental tissue