Ischemia-reperfusion injury — Flashcards

Flashcard 1: Hyperplastic arteriolosclerosis may lead to _____ necrosis of the vessel wall with hemorrhage

Answer: fibrinoid

Flashcard 2: What cause of free radical injury occurs following thrombolytic therapy? _____

Answer: Reperfusion injury

Flashcard 3: Leakage of cytosolic enzymes into the serum is a characteristic of _____ cell injury

Answer: irreversible

Flashcard 4: After 30 minutes of total myocardial ischemia, is ischemic injury reversible?_____

Answer: No

Flashcard 5: Mitochondrial _____ signifies irreversible cellular injury

Answer: vacuolization

Flashcard 6: What type of infarct occurs with venous occlusion, tissues with multiple blood supplies (e.g. liver, lungs, intestine, testes), or reperfusion? _____

Answer: Red (hemorrhagic) infarct

Flashcard 7: Which mechanism of cell death is an inflammatory process? _____

Answer: Necrosis

Flashcard 8: Niemann Pick disease may present with progressive _____

Answer: neurodegeneration

Extra:   https://onlinemeded.org/spa/metabolism?ref=anki 

Flashcard 9: Fat necrosis of breast tissue presents as a painless _____ on physical exam

Answer: mass

Extra:   * Necrosis may be tender and painful, as well; "irregular breast mass" Watch Benign Breast Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-reproductive-gu/videos/medical-pathophysiology-reproductive-and-gu-breast-benign-breast-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/inflammation-and-neoplasia/necrosis/acquire?ref=anki 

Flashcard 10: Which layer of the cerebellum is most affected by global cerebral ischemia? _____

Answer: Purkinje layer

Extra:  Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/ischemic-cerebrovascular-accidents?index=2] https://onlinemeded.org?ref=anki Atlas: