Apoptosis pathways — Flashcards

Flashcard 1: Which mechanism of cell death involves death of single cells or small groups of cells? _____

Answer: Apoptosis

Flashcard 2: The morphologic hallmark of cell death is loss of the _____

Answer: nucleus

Flashcard 3: The nucleus of apoptotic cells stains deeply _____-philic

Answer: baso

Flashcard 4: Which mechanism of cell death is an inflammatory process? _____

Answer: Necrosis

Flashcard 5: Which mechanism of cell death involves death of a large group of cells? _____

Answer: Necrosis

Flashcard 6: _____ is a misfolded protein that deposits in the extracellular space, resulting in cellular damage and apoptosis

Answer: Amyloid

Flashcard 7: Fat necrosis of breast tissue presents as a painless _____ on physical exam

Answer: mass

Extra:   * Necrosis may be tender and painful, as well; "irregular breast mass" Watch Benign Breast Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-reproductive-gu/videos/medical-pathophysiology-reproductive-and-gu-breast-benign-breast-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/inflammation-and-neoplasia/necrosis/acquire?ref=anki 

Flashcard 8: Niemann Pick disease may present with progressive _____

Answer: neurodegeneration

Extra:   https://onlinemeded.org/spa/metabolism?ref=anki 

Flashcard 9: Which layer of the cerebellum is most affected by global cerebral ischemia? _____

Answer: Purkinje layer

Extra:  Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/ischemic-cerebrovascular-accidents?index=2] https://onlinemeded.org?ref=anki Atlas: 

Flashcard 10: Ionizing radiation results in the formation of double-stranded breaks in DNA and _____ which damage DNA

Answer: hydroxyl free radicals

Extra:   https://onlinemeded.org?ref=anki