Antiviral agents and mechanisms — Flashcards

Flashcard 1: _____ is a Herpesvirus that is latent in mononuclear cells.

Answer: CMV

Flashcard 2: Which class of helper T cell secretes IFN- and IL-2? _____

Answer: Th1

Flashcard 3: What viruses (2) can be diagnosed with a Tzank smear?_____

Answer: VZV and HSV

Flashcard 4: Picornavirus have viral _____ which cleave the large translated polypeptide into functional viral proteins

Answer: proteases

Flashcard 5: Herpes Simplex Virus (HSV) replicates in the _____

Answer: nucleus (cytoplasm or nucleus)

Flashcard 6: Caliciviruses produce one polypeptide product that is cleaved via _____

Answer: viral proteases

Flashcard 7: What type of viruses are picornaviruses? (DNA, RNA (sense), etc)_____

Answer: Positive sense RNA

Flashcard 8: Which DNA virus preferentially infects erythroid progenitors? _____

Answer: Parvovirus B19

Extra:    https://onlinemeded.org/spa/microbiology/dna-viruses/acquire?ref=anki 

Flashcard 9: Which immunoglobulin is released into secretions (tears, saliva, mucus)? _____

Answer: IgA

Extra:  Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/antibodies?index=6] https://onlinemeded.org/spa/immunology?ref=anki 

Flashcard 10: Which virus is associated with outbreaks on cruise ships? _____

Answer: Norovirus (norwalk virus)

Extra:  Watch Norovirus/Norwalk virus (Caliciviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-rna-viruses-positive-sense-norovirusnorwalk-virus-caliciviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease?ref=anki