Oncogenic viruses — Flashcards

Flashcard 1: What is the cancer risk associated with HPV6? _____

Answer: Low

Extra:    https://onlinemeded.org/spa/microbiology/dna-viruses/acquire?ref=anki 

Flashcard 2: What do the vaccines for HPV 6, 11, 16, 18, target? _____ of the virus

Answer: Capsid proteins

Extra:   Watch Human papillomavirus (Papillomaviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-dna-viruses-human-papillomavirus-papillomaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/pediatrics/vaccinations/acquire?ref=anki 

Flashcard 3: Which oncogenic microbe is associated with the following cancers?: _____ Cervical and Penile / Anal Carcinoma Head and Neck Cancer

Answer: HPV

Extra:  Watch Bladder Cancer & Penile Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-reproductive-gu/videos/medical-pathophysiology-reproductive-and-gu-male-gu-bladder-cancer-and-penile-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/histology/videos/female-reproductive-system?index=13] https://onlinemeded.org/spa/gynecology/cervical-cancer/acquire?ref=anki  

Flashcard 4: _____ carcinoma is a complication of Epstein-Barr Virus in patients of Asian descent

Answer: Nasopharyngeal

Extra:    https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 5: What are 4 characteristics of HPV itself? _____

Answer: Non-enveloped (naked), icosahedral, circular, dsDNA virus

Extra:   Watch Human papillomavirus (Papillomaviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-dna-viruses-human-papillomavirus-papillomaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/gynecology/cervical-cancer/acquire?ref=anki 

Flashcard 6: What type of virus is HHV-8? _____

Answer: Double-stranded DNA

Extra:    https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 7: What virus is nasopharyngeal carcinoma associated with? _____

Answer: Epstein-Barr Virus (EBV)

Extra:  https://onlinemeded.org?ref=anki 

Flashcard 8: HHV-8 causes _____

Answer: Kaposi Sarcoma

Extra:    https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki 

Flashcard 9: Epstein-Barr virus (EBV) primarily infects the _____, liver, and B cells

Answer: oropharynx

Extra:  https://onlinemeded.org/spa/hematology-oncology/leukemia/acquire?ref=anki Atlas: 

Flashcard 10: What are the most common types of high-risk HPV? _____

Answer: HPV16; HPV18

Extra:   Watch Human papillomavirus (Papillomaviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-dna-viruses-human-papillomavirus-papillomaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch Cervical Neoplasia [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-dna-viruses-human-papillomavirus-papillomaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/gynecology/cervical-cancer/acquire?ref=anki 

Flashcard 11: Which layer of the epithelium does HPV infect? _____

Answer: Stratum basale

Extra:   Watch Human papillomavirus (Papillomaviridae) [https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-viruses/videos/medical-microbiology-viruses-dna-viruses-human-papillomavirus-papillomaviridae?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch Cervical Neoplasia [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-metabolism/videos/medical-biochemistry-metabolism-carbohydrates-gluconeogenesis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/gynecology/cervical-cancer/acquire?ref=anki 

Flashcard 12: Epstein-Barr virus (EBV) remains dormant in _____ cells, which increases risk for lymphoma, especially if immunodeficiency develops (e.g. HIV)

Answer: B

Extra:  https://onlinemeded.org/spa/hematology-oncology/leukemia/acquire?ref=anki Atlas: 

Flashcard 13: HHV-8 causes _____

Answer: Kaposi Sarcoma

Extra:  https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki 

Flashcard 14: Where is EBV latent?_____

Answer: B cells

Flashcard 15: Viruses such as EBV, HHV-8, HBV/HCV, etc are said to be _____ viruses due to them causing cancer

Answer: oncogenic

Flashcard 16: What is the cancer risk associated with HPV6?_____

Answer: Low

Flashcard 17: Which oncogenic microbe is associated with the following cancers?:_____Lymphomas (ex. Endemic Burkitt Lymphoma)Nasopharyngeal CarcinomaPrimary CNS Lymphoma (in AIDS)Posttransplant Lymphoproliferative Disease

Answer: EBV

Flashcard 18: What is the cancer risk associated with HPV31?_____

Answer: High

Flashcard 19: What are 4 characteristics of HPV itself?_____

Answer: Non-enveloped (naked), icosahedral, circular, dsDNA virus (enveloped?, shape?, circular/linear?, DNA/RNA?)

Flashcard 20: What types of HPV encode for the proteins E6 and E7?_____

Answer: High Risk (HPV 16, 18, 31, 33)

Flashcard 21: What microbe can increase the risk of penile/anal carcinoma?_____

Answer: High risk HPV

Flashcard 22: Which Herpesvirus is associated with Nasopharyngeal Carcinoma?_____

Answer: EBV