NRTI, NNRTI, PI, INSTI, and entry inhibitors US Medical PG Flashcards - Medical Study Cards
Master NRTI, NNRTI, PI, INSTI, and entry inhibitors with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
NRTI, NNRTI, PI, INSTI, and entry inhibitors Flashcard Deck - 10 Cards
Flashcard 1: HIV initially infects what cell type?_____
Answer: Macrophages
Flashcard 2: Which gene is mutated in HIV protease inhibitor resistance?_____
Answer: pol gene
Flashcard 3: Which enzyme allows for HIV dsDNA to integrate with host cell DNA?_____
Answer: Integrase
Flashcard 4: Which viral gene in HIV codes for its Aspartate Protease?_____
Answer: pol
Flashcard 5: What infectious disease is an irreversible cause of dementia? _____
Answer: HIV
Flashcard 6: Which viral gene in HIV codes for its Integrase?_____
Answer: pol
Flashcard 7: progressive multifocal leukoencephalopathy (PML)
Answer:
Extra: destruction of oligodendrocytes, demyelination of CNSrapidly progressive, usually fatalrecent JC virus infection, AIDS
Flashcard 8: The _____ blot *used to be* the confirmatory test for HIV after a positive ELISA
Answer: Western
Extra:
https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki
Flashcard 9: Which envelope protein on HIV binds the CD4 molecule and a chemokine receptor (CXCR4 or CCR5)?
_____
Answer: gp120
Extra:
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
Flashcard 10: Which HIV gene encodes for the virion p24 (Capsid) and p17 (Matrix) core proteins?
_____
Answer: gag
Extra:
https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki
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