Hemolytic anemias — Flashcards

Flashcard 1: G6PD deficiency is a cause of _____ (MCV) anemia

Answer: normocytic

Flashcard 2: Which form of autoimmune hemolytic anemia (IgG or IgM) causes painful, blue fingers and toes with cold exposure? _____

Answer: IgM (cold agglutinin)

Flashcard 3: Which blood transfusion reaction presents with fever, hypotension, tachypnea, hemoglobinuria*, and jaundice? _____

Answer: Acute hemolytic transfusion reaction

Flashcard 4: Paroxysmal nocturnal hemoglobinuria is primarily characterized by _____ hemolysis

Answer: intravascular

Flashcard 5: _____ is defined as a reduction in circulating red blood cell (RBC) mass

Answer: Anemia

Flashcard 6: Does sickle cell anemia result in extravascular or intravascular hemolysis?_____

Answer: Both

Flashcard 7: In red blood cells, lack of ATP impairs membrane integrity due to lack of cation transport, causing an _____ anemia

Answer: extravascular hemolytic

Flashcard 8: priapism

Answer: spinal trauma, sickle cell disease, medications

Extra: painful, sustained erection not associated with sexual desire or stimulation

Flashcard 9: hemorrhagic stroke

Answer:

Extra: HTN, anticoagulation, neoplasia, recent ischemic stroke

Flashcard 10: hereditary hemorrhagic telangectasia (Osler-Weber-Rendu syndrome)

Answer:

Extra: telangectasia, recurrent epistaxis, skin discolorations, arteriovenous malformations (AVMs)AD