Urea cycle reactions and enzymes US Medical PG Flashcards - Medical Study Cards
Master Urea cycle reactions and enzymes with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Urea cycle reactions and enzymes Flashcard Deck - 10 Cards
Flashcard 1: Hyperammonemia results in excess NH3, which depletes _____, leading to inhibition of the TCA cycle
Answer: -ketoglutarate
Flashcard 2: Where in the cell is the carbamoyl phosphate synthetase I enzyme found?_____
Answer: Mitochondria (urea cycle)
Flashcard 3: Ornithine transcarbamylase (OTC) deficiency presents with increased _____ acid in the blood and urine
Answer: orotic
Flashcard 4: Carbamoyl phosphate synthetase I is regulated via positive feedback by _____
Answer: N-acetylglutamate
Flashcard 5: What is the most common urea cycle disorder? _____
Answer: Ornithine transcarbamylase (OTC) deficiency
Flashcard 6: Disorders of the urea cycle interfere with the body's ability to eliminate _____
Answer: ammonia (NH3)
Flashcard 7: Where does the urea cycle occur?
Answer: steps in both the cytoplasm and mitochondria
Flashcard 8: urea cycle
Answer: carbomoyl phosphate synthetase I
Flashcard 9: What is the overall purpose of the urea cycle?
Answer: to get NH4+ from amino acid catabolism into an excretable form
Flashcard 10: carbomoyl phosphate synthetase I
Answer: urea cycle
Extra: N-acetylglutamate
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