Hyperammonemia results in excess NH3, which depletes _____, leading to inhibition of the TCA cycle
#2
What is the major transport form of NH3 in the blood (from most tissues)? _____
#3
Most disorders of the urea cycle require _____ as an essential amino acid, particularly during episodes of hyperammonemia
#4
Which tissue/organ uses alanine as its major transport form of NH3? _____
#5
The NH3 in the intestine may be transported to the liver in the form of _____ in the portal blood
#6
What class of enzymes is used in the transfer of NH3 groups during nitrogen metabolism?_____
#7
When an amino acid is metabolized, it is broken down into a carbon skeleton and _____ (highly toxic)
#8
Where does the urea cycle occur?
#9
urea cycle
#10
What is the overall purpose of the urea cycle?
Nitrogen sources and transport forms US Medical PG Flashcards - Medical Study Cards
Master Nitrogen sources and transport forms with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Nitrogen sources and transport forms Flashcard Deck - 10 Cards
Flashcard 1: Hyperammonemia results in excess NH3, which depletes _____, leading to inhibition of the TCA cycle
Answer: -ketoglutarate
Flashcard 2: What is the major transport form of NH3 in the blood (from most tissues)? _____
Answer: Glutamine
Flashcard 3: Most disorders of the urea cycle require _____ as an essential amino acid, particularly during episodes of hyperammonemia
Answer: arginine
Flashcard 4: Which tissue/organ uses alanine as its major transport form of NH3? _____
Answer: Muscle
Flashcard 5: The NH3 in the intestine may be transported to the liver in the form of _____ in the portal blood
Answer: NH3
Flashcard 6: What class of enzymes is used in the transfer of NH3 groups during nitrogen metabolism?_____
Answer: Aminotransferases
Flashcard 7: When an amino acid is metabolized, it is broken down into a carbon skeleton and _____ (highly toxic)
Answer: NH3
Flashcard 8: Where does the urea cycle occur?
Answer: steps in both the cytoplasm and mitochondria
Flashcard 9: urea cycle
Answer: carbomoyl phosphate synthetase I
Flashcard 10: What is the overall purpose of the urea cycle?
Answer: to get NH4+ from amino acid catabolism into an excretable form
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