Protein folding and chaperones US Medical PG Flashcards - Medical Study Cards
Master Protein folding and chaperones with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Protein folding and chaperones Flashcard Deck - 10 Cards
Flashcard 1: _____ are abundant, cytosolic ribonucleoproteins that traffic proteins from the ribosome to the RER
Answer: Signal recognition particles (SRPs)
Flashcard 2: One class of post-translational modifications is _____, which include phosphorylation, glycosylation, hydroxylation, methylation, acetylation, and ubiquitination
Answer: covalent alterations
Flashcard 3: The bond formed between an -carboxyl group and an -amino group of adjacent amino acids is a _____
Answer: peptide bond
Flashcard 4: Genetic mutations often result in the cellular production of abnormal proteins, which are expressed on _____ molecules
Answer: MHC class I
Flashcard 5: On the N terminal side of newly synthesized protein, a stretch of 10-15 hydrophobic amino acids forms the _____ sequence
Answer: N-terminal signal
Flashcard 6: Where does protein synthesis take place?
Answer: RER
Flashcard 7: ribosome
Answer: protein synthesis
Extra: 50S and 30S subunits
Flashcard 8: Northern
Answer: RNA
Extra: complementary labeled RNA
Flashcard 9: What occurs during the translation step of collagen synthesis?
Answer: translation of preprocollagen α-chains
Flashcard 10: What kinds of proteins are synthesized by membrane bound ribosomes vs. free ribosomes?
Answer: membrane-bound - secretory proteins
free - cytosolic and organellar
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