WNT signaling pathway US Medical PG Flashcards - Medical Study Cards
Master WNT signaling pathway with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
WNT signaling pathway Flashcard Deck - 10 Cards
Flashcard 1: What is the mechanism that results in malignancy from the RAS oncogene?_____
Answer: point mutation
Flashcard 2: What type of oncogene is RAS?_____
Answer: GTP-binding protein (signal transducer)
Flashcard 3: Tumor suppressor genes _____ cell growth
Answer: regulate
Flashcard 4: MUTYH-associated polyposis is an _____ syndrome with multiple colorectal adenomas and an increased risk of colorectal cancer.
Answer: autosomal recessive (inheritance)
Flashcard 5: Which tumor suppressor genes are associated with colon cancer?_____
Answer: DCC, APC
Flashcard 6: NADPH oxidase
Answer: respiratory burst
Extra: O2 O2-
Flashcard 7: Give the pathway by which glucagon/Epi regulate glycogen.
Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase
Flashcard 8: Give the pathway by which insulin regulates glycogen.
Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase
Flashcard 9: If an enyzme is a kinase, what do you know about its function?
Answer: uses ATP to add phosphate group to substrate
Flashcard 10: How does a direct enzyme-linked immunosorbent assay (ELISA) work?
Answer: 1. Patient's blood sample washed over a fixed antibody linked to a color-generating enzyme.
2. Any antibody-antibody-enzyme complex produces color change.
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