TGF-β/SMAD signaling US Medical PG Flashcards - Medical Study Cards
Master TGF-β/SMAD signaling with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
TGF-β/SMAD signaling Flashcard Deck - 10 Cards
Flashcard 1: What type of receptor do growth hormones use for their signaling pathways? _____
Answer: Receptor associated tyrosine kinases
Flashcard 2: Which tumor suppressor genes are associated with colon cancer?_____
Answer: DCC, APC
Flashcard 3: What is the primary role of fibroblast growth factor (FGF-2)? _____
Answer: Angiogenesis
Flashcard 4: The APC tumor suppresor regulates the Wnt signalling pathway by destroying _____ in the absence of a Wnt receptor-ligand interaction
Answer: B-catenin
Flashcard 5: What type of oncogene is ABL?_____
Answer: Tyrosine kinase (signal transducer)
Flashcard 6: What protein in hemidesmosomes binds to fibronectin, laminin, or collagen in the basement membrane? _____ *bonus-Ca2+ dependent? Y/N
Answer: Integrin
Flashcard 7: NADPH oxidase
Answer: respiratory burst
Extra: O2 O2-
Flashcard 8: Give the pathway by which glucagon/Epi regulate glycogen.
Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase
Flashcard 9: Give the pathway by which insulin regulates glycogen.
Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase
Flashcard 10: If an enyzme is a kinase, what do you know about its function?
Answer: uses ATP to add phosphate group to substrate
Keywords: TGF-β/SMAD signaling flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
