Second messenger systems (cAMP, cGMP, Ca2+) US Medical PG Flashcards - Medical Study Cards
Master Second messenger systems (cAMP, cGMP, Ca2+) with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Second messenger systems (cAMP, cGMP, Ca2+) Flashcard Deck - 10 Cards
Flashcard 1: _____ proteins are specific transcription factors that bind to cAMP response elements (CREs) to cause a response to cAMP
Answer: cAMP response element binding (CREB)
Flashcard 2: Pertussis toxin ribosylates Gi, _____ the G-protein receptor (activating or inhibiting)
Answer: inhibiting
Flashcard 3: What hormone acts through a receptor guanylyl cyclase? _____
Answer: Atrial natriuretic peptide (ANP)
Flashcard 4: What type of receptor do growth hormones use for their signaling pathways? _____
Answer: Receptor associated tyrosine kinases
Flashcard 5: After the subunit is bound by GTP (cellular signaling), the -GTP subunit _____ from its respective G protein (i.e. Gs, Gi, or Gq)
Answer: detaches
Flashcard 6: TRH acts on which signalling cascade? _____
Answer: IP3
Flashcard 7: NADPH oxidase
Answer: respiratory burst
Extra: O2 O2-
Flashcard 8: Give the pathway by which glucagon/Epi regulate glycogen.
Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase
Flashcard 9: Give the pathway by which insulin regulates glycogen.
Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase
Flashcard 10: If an enyzme is a kinase, what do you know about its function?
Answer: uses ATP to add phosphate group to substrate
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