PI3K-Akt pathway US Medical PG Flashcards - Medical Study Cards
Master PI3K-Akt pathway with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
PI3K-Akt pathway Flashcard Deck - 10 Cards
Flashcard 1: mTOR is a _____
Answer: protooncogene (protooncogene or tumorsuppressor?)
Flashcard 2: Tumor suppressor genes _____ cell growth
Answer: regulate
Flashcard 3: What type of receptor do growth hormones use for their signaling pathways? _____
Answer: Receptor associated tyrosine kinases
Flashcard 4: What type of oncogene is ABL?_____
Answer: Tyrosine kinase (signal transducer)
Flashcard 5: NADPH oxidase
Answer: respiratory burst
Extra: O2 O2-
Flashcard 6: Give the pathway by which glucagon/Epi regulate glycogen.
Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase
Flashcard 7: Give the pathway by which insulin regulates glycogen.
Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase
Flashcard 8: If an enyzme is a kinase, what do you know about its function?
Answer: uses ATP to add phosphate group to substrate
Flashcard 9: How does a direct enzyme-linked immunosorbent assay (ELISA) work?
Answer: 1. Patient's blood sample washed over a fixed antibody linked to a color-generating enzyme.
2. Any antibody-antibody-enzyme complex produces color change.
Flashcard 10: What is the function of cyclin proteins?
Answer: regulate cell cycle; concentrations are cyclic and phase-dependent, complex with and activate CDKs
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