Pharmacological targeting of signaling pathways US Medical PG Flashcards - Medical Study Cards
Master Pharmacological targeting of signaling pathways with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Pharmacological targeting of signaling pathways Flashcard Deck - 10 Cards
Flashcard 1: Growth factor receptors are _____ (receptor class)
Answer: receptor tyrosine kinases
Flashcard 2: What class of protein receptor is common to cAMP response element binding (CREB) proteins? _____
Answer: Leucine zipper
Flashcard 3: Steroid receptors are specific transcription factors that bind to _____ to cause a steroid response
Answer: steroid response elements
Flashcard 4: Pertussis toxin ribosylates Gi, _____ the G-protein receptor (activating or inhibiting)
Answer: inhibiting
Flashcard 5: What type of receptor do growth hormones use for their signaling pathways? _____
Answer: Receptor associated tyrosine kinases
Flashcard 6: After the subunit is bound by GTP (cellular signaling), the -GTP subunit _____ from its respective G protein (i.e. Gs, Gi, or Gq)
Answer: detaches
Flashcard 7: NADPH oxidase
Answer: respiratory burst
Extra: O2 O2-
Flashcard 8: Give the pathway by which glucagon/Epi regulate glycogen.
Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase
Flashcard 9: Give the pathway by which insulin regulates glycogen.
Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase
Flashcard 10: If an enyzme is a kinase, what do you know about its function?
Answer: uses ATP to add phosphate group to substrate
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