Nuclear receptor signaling US Medical PG Flashcards - Medical Study Cards
Master Nuclear receptor signaling with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Nuclear receptor signaling Flashcard Deck - 10 Cards
Flashcard 1: Androgen insensitivity syndrome is caused by a deficiency of _____ in target tissues of males
Answer: androgen receptors
Flashcard 2: Steroid receptors are specific transcription factors that bind to _____ to cause a steroid response
Answer: steroid response elements
Flashcard 3: What class of protein receptor is common to all steroid hormones, thyroid hormones, and vitamins A/D? _____
Answer: Zinc finger
Flashcard 4: How do the receptors bound by steroid and thyroid hormones differ from the receptors bound by peptide hormones?_____
Answer: Peptide hormones bind extracellular receptors
Flashcard 5: Once a steroid hormone has bound its receptor in the cytoplasm or nucleus, the hormone-receptor complex then _____
Answer: dimerizes
Flashcard 6: Placental _____ deficiency is the inability to synthesize estrogens from androgens
Answer: aromatase
Flashcard 7: Within an enhancer, there are domains known as _____, to which specific transcription factors bind
Answer: response elements (RE)
Flashcard 8: NADPH oxidase
Answer: respiratory burst
Extra: O2O2-
Flashcard 9: Give the pathway by which glucagon/Epi regulate glycogen.
Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase
Flashcard 10: Give the pathway by which insulin regulates glycogen.
Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase
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