NF-κB signaling US Medical PG Flashcards - Medical Study Cards
Master NF-κB signaling with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
NF-κB signaling Flashcard Deck - 10 Cards
Flashcard 1: _____ is an arachidonic acid pathway metabolite that causes neutrophil chemotaxis
Answer: LTB4
Flashcard 2: Endotoxin triggers the release of which two cytokines?_____
Answer: TNF and IL-1
Flashcard 3: What type of oncogene is c-MYC, N-MYC, L-MYC?_____
Answer: Transcription factor (nuclear regulator)
Flashcard 4: NADPH oxidase
Answer: respiratory burst
Extra: O2 O2-
Flashcard 5: Give the pathway by which glucagon/Epi regulate glycogen.
Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase
Flashcard 6: Give the pathway by which insulin regulates glycogen.
Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase
Flashcard 7: If an enyzme is a kinase, what do you know about its function?
Answer: uses ATP to add phosphate group to substrate
Flashcard 8: How does a direct enzyme-linked immunosorbent assay (ELISA) work?
Answer: 1. Patient's blood sample washed over a fixed antibody linked to a color-generating enzyme.
2. Any antibody-antibody-enzyme complex produces color change.
Flashcard 9: What is the function of cyclin proteins?
Answer: regulate cell cycle; concentrations are cyclic and phase-dependent, complex with and activate CDKs
Flashcard 10: When during the cell cycle are CDKs produced?
Answer: always; CDKs are constitutively expressed but inactive without the correct cyclin hence "cyclin-dependent"
Keywords: NF-κB signaling flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
