MAP kinase pathways US Medical PG Flashcards - Medical Study Cards
Master MAP kinase pathways with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
MAP kinase pathways Flashcard Deck - 10 Cards
Flashcard 1: Growth factor receptors are _____ (receptor class)
Answer: receptor tyrosine kinases
Flashcard 2: What is the mechanism that results in malignancy from the RAS oncogene?_____
Answer: point mutation
Flashcard 3: What type of oncogene is RAS?_____
Answer: GTP-binding protein (signal transducer)
Flashcard 4: What type of receptor do growth hormones use for their signaling pathways? _____
Answer: Receptor associated tyrosine kinases
Flashcard 5: The NF1 tumor suppressor gene normally codes for neurofibromin, a negative regulator of _____
Answer: RAS
Flashcard 6: What type of oncogene is ALK?_____
Answer: receptor tyrosine kinase
Flashcard 7: Activated Ras (Ras-_____ complex) sends signals to the nucleus
Answer: GTP
Flashcard 8: NADPH oxidase
Answer: respiratory burst
Extra: O2 O2-
Flashcard 9: Give the pathway by which glucagon/Epi regulate glycogen.
Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase
Flashcard 10: Give the pathway by which insulin regulates glycogen.
Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase
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