Hedgehog signaling pathway US Medical PG Flashcards - Medical Study Cards
Master Hedgehog signaling pathway with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Hedgehog signaling pathway Flashcard Deck - 10 Cards
Flashcard 1: Holoprosencephaly may be related to mutations in the _____ signaling pathway
Answer: sonic hedgehog
Flashcard 2: Targets of JAK (tyrosine kinase associated-receptor pathway) include _____, which cause transcription of new mRNAs and new protein synthesis
Answer: STATs
Flashcard 3: Mutations in which tumor suppressor genes can lead to Tuberous Sclerosis?_____
Answer: TSC1 & TSC2
Flashcard 4: Do noncompetitive inhibitors resemble the substrate?_____
Answer: No
Flashcard 5: _____ growth factor stimulates cell growth via tyrosine kinases
Answer: Epidermal
Flashcard 6: What type of oncogene is ABL?_____
Answer: Tyrosine kinase (signal transducer)
Flashcard 7: NADPH oxidase
Answer: respiratory burst
Extra: O2 O2-
Flashcard 8: Give the pathway by which glucagon/Epi regulate glycogen.
Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase
Flashcard 9: Give the pathway by which insulin regulates glycogen.
Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase
Flashcard 10: If an enyzme is a kinase, what do you know about its function?
Answer: uses ATP to add phosphate group to substrate
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