_____ is a genome editing tool that is derived from bacteria to knock in / out any DNA sequence
#3
A _____ transgenic mouse has had a gene inserted
#4
_____ uses a fluorescent DNA/RNA probe to bind to a specific gene of interest on chromosomes
#5
What is the mode of inheritance of SCID secondary to a defective IL-2R? _____
#6
A _____ is a type of DNA mutation in which a purine is mutated into a pyrimidine, and vice versa
#7
What triplet is associated with Huntington's disease?
#8
What triplet is associated with Fragile X syndrome?
#9
What triplet is associated with myotonic dystrophy?
#10
Uniparental isodisomy indicates an error in what process?
Gene therapy approaches US Medical PG Flashcards - Medical Study Cards
Master Gene therapy approaches with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Gene therapy approaches Flashcard Deck - 10 Cards
Flashcard 1: A _____ transgenic mouse has had a gene removed
Answer: knock-out
Flashcard 2: _____ is a genome editing tool that is derived from bacteria to knock in / out any DNA sequence
Answer: CRISPR/Cas9
Flashcard 3: A _____ transgenic mouse has had a gene inserted
Answer: knock-in
Flashcard 4: _____ uses a fluorescent DNA/RNA probe to bind to a specific gene of interest on chromosomes
Answer: Fluorescence in situ hybridization (FISH)
Flashcard 5: What is the mode of inheritance of SCID secondary to a defective IL-2R? _____
Answer: X-linked
Flashcard 6: A _____ is a type of DNA mutation in which a purine is mutated into a pyrimidine, and vice versa
Answer: transversion
Flashcard 7: What triplet is associated with Huntington's disease?
Answer: CAG
mnemonic: X-Girlfriend's First Aid Helped Ace My Test
Flashcard 8: What triplet is associated with Fragile X syndrome?
Answer: CGG
mnemonic: X-Girlfriend's First Aid Helped Ace My Test
Flashcard 9: What triplet is associated with myotonic dystrophy?
Answer: CTG
mnemonic: X-Girlfriend's First Aid Helped Ace My Test
Flashcard 10: Uniparental isodisomy indicates an error in what process?
