Pay-off phase reactions — Flashcards

Flashcard 1: Pyruvate kinase defiency results in increased levels of _____, which causes decreased Hb affinity for O2

Answer: 2,3-BPG

Flashcard 2: Conversion of 1,3-BPG into 3-phosphoglycerate (glycolysis) produces a molecule of _____

Answer: ATP

Flashcard 3: Pyruvate kinase deficiency presents with _____ levels of 2,3-BPG

Answer: increased

Flashcard 4: Which steps (2) of glycolysis require ATP? _____

Answer:

Flashcard 5: What substrate overrides inhibition of the enzyme phosphofructokinase-1 by ATP in the liver? _____

Answer: Fructose-2,6-bisphosphate

Flashcard 6: What is the only metabolic pathway for generating ATP, anaerobically? _____

Answer: Glycolysis

Flashcard 7: phosphofructokinase-2/fructose bisphosphatase-2 (PFK-2/FBP-2)

Answer:

Extra: balances glycolysis and gluconeogenesisF-2,6-BP

Flashcard 8: Where does glycolysis take place?

Answer: cytoplasm

Flashcard 9: glycolysis

Answer: phosphofructokinase-1 (PFK-1)

Flashcard 10: What enzyme converts pyruvate to lactate?

Answer: lactate dehydrogenase (LDH)