Overview and regulation of glycolysis — Flashcards

Flashcard 1: Pyruvate kinase defiency results in increased levels of _____, which causes decreased Hb affinity for O2

Answer: 2,3-BPG

Flashcard 2: Which steps (2) of glycolysis produce ATP? _____

Answer:

Flashcard 3: Glucokinase is regulated via negative feedback by _____

Answer: fructose-6-phosphate

Flashcard 4: What substrate overrides inhibition of the enzyme phosphofructokinase-1 by ATP in the liver? _____

Answer: Fructose-2,6-bisphosphate

Flashcard 5: What is the only metabolic pathway for generating ATP, anaerobically? _____

Answer: Glycolysis

Flashcard 6: What is the rate-limiting enzyme of glycolysis?_____

Answer: Phosphofructokinase-1 (PFK-1)

Flashcard 7: phosphofructokinase-2/fructose bisphosphatase-2 (PFK-2/FBP-2)

Answer:

Extra: balances glycolysis and gluconeogenesisF-2,6-BP

Flashcard 8: Where does glycolysis take place?

Answer: cytoplasm

Flashcard 9: glycolysis

Answer: phosphofructokinase-1 (PFK-1)

Flashcard 10: What enzyme converts pyruvate to lactate?

Answer: lactate dehydrogenase (LDH)