Feeder pathways to glycolysis — Flashcards

Flashcard 1: Glyceraldehyde-3-phosphate is converted into _____ via the enzyme glyceraldehyde-3P-dehydrogenase (glycolysis)

Answer: 1,3-bisphosphoglycerate (1,3-BPG)

Flashcard 2: What glycolysis enzyme deficiency causes hemolytic anemia in a newborn?_____

Answer: Pyruvate kinase deficiency

Flashcard 3: Glucokinase is regulated via negative feedback by _____

Answer: fructose-6-phosphate

Flashcard 4: What substrate overrides inhibition of the enzyme phosphofructokinase-1 by ATP in the liver? _____

Answer: Fructose-2,6-bisphosphate

Flashcard 5: Pyruvate kinase is regulated via positive feedback by _____ (glycolysis)

Answer: fructose-1,6-bisphosphate

Flashcard 6: Which glycolysis enzyme deficiency is the second most common cause of hemolytic anemia? _____

Answer: Pyruvate kinase deficiency

Flashcard 7: phosphofructokinase-2/fructose bisphosphatase-2 (PFK-2/FBP-2)

Answer:

Extra: balances glycolysis and gluconeogenesisF-2,6-BP

Flashcard 8: Where does glycolysis take place?

Answer: cytoplasm

Flashcard 9: glycolysis

Answer: phosphofructokinase-1 (PFK-1)

Flashcard 10: What enzyme converts pyruvate to lactate?

Answer: lactate dehydrogenase (LDH)