Disorders of glycolytic enzymes US Medical PG Flashcards - Medical Study Cards
Master Disorders of glycolytic enzymes with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Disorders of glycolytic enzymes Flashcard Deck - 10 Cards
Flashcard 1: Pyruvate kinase defiency results in increased levels of _____, which causes decreased Hb affinity for O2
Answer: 2,3-BPG
Flashcard 2: What glycolysis enzyme deficiency causes hemolytic anemia in a newborn?_____
Answer: Pyruvate kinase deficiency
Flashcard 3: What is the only metabolic pathway for generating ATP, anaerobically? _____
Answer: Glycolysis
Flashcard 4: Pyruvate kinase is regulated via positive feedback by _____ (glycolysis)
Answer: fructose-1,6-bisphosphate
Flashcard 5: What is the rate-limiting enzyme of glycolysis?_____
Answer: Phosphofructokinase-1 (PFK-1)
Flashcard 6: phosphofructokinase-2/fructose bisphosphatase-2 (PFK-2/FBP-2)
Answer:
Extra: balances glycolysis and gluconeogenesis F-2,6-BP
Flashcard 7: Where does glycolysis take place?
Answer: cytoplasm
Flashcard 8: glycolysis
Answer: phosphofructokinase-1 (PFK-1)
Flashcard 9: What enzyme converts pyruvate to lactate?
Answer: lactate dehydrogenase (LDH)
Flashcard 10: glucokinase
Answer: first step of glycolysis and glycogen synthesis
Extra: tag glucose with phosphate so that it is trapped within the cell glucose G6P insulin liver and β cells of pancreas
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