Glycogen structure and metabolism overview US Medical PG Flashcards - Medical Study Cards
Master Glycogen structure and metabolism overview with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Glycogen structure and metabolism overview Flashcard Deck - 10 Cards
Flashcard 1: Which glycogen storage disorder is associated with severe fasting hypoglycemia? _____
Answer: Von Gierke disease
Flashcard 2: Glycogen phosphorylase is regulated via positive feedback by _____ (liver)
Answer: glucagon
Flashcard 3: Dephosphorylation of glycogen synthase causes enzyme _____ (activation/inactivation)
Answer: activation
Flashcard 4: Glucokinase is regulated via positive feedback by _____
Answer: insulin
Flashcard 5: What is the rate-limiting enzyme for glycogenolysis? _____
Answer: Glycogen phosphorylase
Flashcard 6: In skeletal muscle, glycogenolysis ultimately produces _____, which is rapidly metabolized during exercise
Answer: glucose-6-phosphate
Flashcard 7: glycogen synthesis
Answer: glycogen synthase
Flashcard 8: glycogenolysis
Answer: glycogen phosphorylase
Flashcard 9: McArdle's disease (GSD type V)
Answer:
Extra: painful muscle cramps, myoglobinuria with strenuous exercise glycogen accumulation in muscle AR skeletal muscle glycogen phosphorylase mnemonic: Very Bad Carbohydrate Metabolism (the glycogen storage diseases in order)
Flashcard 10: Cori's disease (GSD type III)
Answer:
Extra: hepatomegaly fasting hypoglycemia, increased hepatic glycogen stores, normal blood lactate levels AR glycogen debranching enzyme mnemonic: Very Bad Carbohydrate Metabolism (the glycogen storage diseases in order)
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