Cancer susceptibility and DNA repair US Medical PG Flashcards - Medical Study Cards
Master Cancer susceptibility and DNA repair with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Cancer susceptibility and DNA repair Flashcard Deck - 10 Cards
Flashcard 1: Nonhomologous End Joining (NHEJ) occurs _____ S phase of the cell cycle
Answer: before (before/after?)
Flashcard 2: What phase of the cell cycle do nucleotide excision repairs occur?_____
Answer: G1
Flashcard 3: Xeroderma Pigmentosum is an inherited pathology due to a defective _____ pathway
Answer: Nucleotide Excision Repair
Flashcard 4: When using CRISPR/Cas9 that introduce a double strand break to knock-out target DNA, _____ repair the gap introduced by this Cas9 variant
Answer: nonhomologous end joining enzymes
Flashcard 5: What form of DNA repair fixes mutations induced by UV radiation?_____
Answer: nucleotide excision repair
Flashcard 6: What process is used by mismatch repair enzymes to distinguish between old and new DNA strands in prokaryotes?_____
Answer: DNA methylation
Flashcard 7: What form of DNA repair fixes mutations due to DNA replication errors?_____
Answer: mismatch repair
Flashcard 8: Which base excision repair enzyme is responsible for removing nucleotides at the 5' end?_____
Answer: AP-endonuclease
Flashcard 9: What are the four mechanisms of DNA repair?
Answer: Nuceotide excision repair
Base excision repair
Mismatch repair
Nonhomologous end joining
Flashcard 10: non-homologous end joining
Answer: join 2 dsDNA ends
Extra: double-stranded breaks (when no homologous chromosome is around to use as a guide) ataxia telangiectasia
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