Amino acid transport disorders — Flashcards

Flashcard 1: What vitamin is derived from the amino acid tryptophan?_____

Answer: Vitamin B3 (niacin)

Flashcard 2: Which bidirectional insulin-independent transporter is found in the beta-islet cells, liver, kidney, and small intestine?_____

Answer: GLUT2

Flashcard 3: _____ disease is characterized by neutral aminoaciduria and decreased neutral AA absorption (esp. tryptophan) from the gut

Answer: Hartnup

Flashcard 4: Dietary ingestion of which amino acids (3) should be restricted in patients with maple syrup urine disease? _____

Answer: Leucine, Isoleucine, Valine

Flashcard 5: What is the mode of inheritance of Hartnup disease? _____

Answer: Autosomal recessive

Flashcard 6: What is the mode of inheritance of cystinuria? _____

Answer: Autosomal recessive (1:7000, common)

Flashcard 7: What stainable protein is abundant in astrocytes?

Answer: GFAP

Flashcard 8: What enzyme converts pyruvate to alanine?

Answer: alanine aminotransferase (ALT)

Flashcard 9: myeloperoxidase

Answer: respiratory burst

Extra: H2O2HOClPMNs

Flashcard 10: superoxide dismutase

Answer: respiratory burst

Extra: O2-H2O2