Rheumatology & Haematology — Flashcards

Chronic myeloid leukemia is usually insidious in onset and seen in _____

Hint: demographic

Accelerated phase of CML presents with fatigue because of _____

How does _____ affect cells? ↑ Erythrocytosis with or without ↑ granulocytosis or thrombocytosis

Hint: myeloproliferative disorder

What is the first-line management of chronic myeloid leukaemia that is used regardless of the phase? _____

Polycythaemia vera is a form of _____ polycythemia

Hint: primary or secondary

The t(9;22) translocation (BCR-ABL) is also known as the _____ chromosome most commonly seen in chronic myeloid leukaemia (CML)

Secondary polycythaemia is characterised by _____ O2 saturation %

What are the confirmatory investigations for polycythaemia vera? _____

Hint: 2

High-risk polycythaemia vera can be managed with _____ alongside low-dose aspirin & venesection

Chronic phase of CML can be asymptomatic, when symptomatic it presents with _____