Calcium and Phosphate Homeostasis — Flashcards

In bone, 1,25-(OH)2 D3 acts syngergistically with PTH to stimulate _____ activity and bone resorption

PTH increases production of _____ activity by stimulating 1-alpha-hydroxylase in the kidney.

In bone, the long-term effect of PTH is bone _____ via indirect action on osteoclasts

The actions of PTH are coordinated to produce an increase in serum _____ and a decrease in serum phosphate (PO43-)

Calcitriol increases _____ of Ca2+ and absorption of phosphate in the intestine.

Chronic exposure of PTH stimulates osteoblasts to express _____, which binds to RANK on osteoclast surfaces to increase activity

_____ is characterized by normal calcium, phosphorus, alkaline phosphatase and parathyroid hormone levels.

Calcitriol _____ Ca2+ and phosphate release into the bloodstream by stimulating osteoblasts to activate osteoclasts

Prolactin deficiency occurs with destruction of the _____ and results in the failure to lactate (females)

The zona _____ secretes androgens, such as dehydroepiandrosterone (DHEA) and androstenedione