Genetic Basis of Drug Response — Flashcards

Genetic Basis of Drug Response — Flashcards

Genetic Basis of Drug Response — Flashcards
#1

Patients with POAG and their offspring and siblings are more likely to be steroid _____

#2

_____ is a urinary antiseptic that can trigger hemolysis in G6PD deficiency patients.

#3

Which gene mutation can confer resistance to ganciclovir, cidofovir, and foscarnet?_____

#4

_____ is the MC gene responsible for isoniazid resistance

#5

Metabolism of warfarin is affected by polymorphisms in the genes for _____ and CYP2C9 (p450 enzyme which metabolizes warfarin)

#6

Which antimalarials (4) can cause hemolysis in G6PD?_____, Artesunate, Dapsone, Quinidine

#7

Sulfa drugs are contraindicated in _____, as they can precipitate hemolytic anemia

#8

Patient with normal pseudocholinesterase has a dibucaine number of _____

#9

_____ injection, an antisense oligonucleotide, is used in rx of DMD in patients who have a confirmed mutation of the DMD gene that is amenable to exon 45 skipping

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