Which antimalarials (4) can cause hemolysis in G6PD?_____, Artesunate, Dapsone, Quinidine
#2
Which gene mutation can confer resistance to ganciclovir, cidofovir, and foscarnet?_____
#3
Metabolism of warfarin is affected by polymorphisms in the genes for _____ and CYP2C9 (p450 enzyme which metabolizes warfarin)
#4
_____ is the MC gene responsible for isoniazid resistance
#5
_____ is a urinary antiseptic that can trigger hemolysis in G6PD deficiency patients.
#6
Sulfa drugs are contraindicated in _____, as they can precipitate hemolytic anemia
#7
Patient with normal pseudocholinesterase has a dibucaine number of _____
#8
_____ injection, an antisense oligonucleotide, is used in rx of DMD in patients who have a confirmed mutation of the DMD gene that is amenable to exon 45 skipping
Cytochrome P450 Polymorphisms Indian Medical PG Flashcards - Medical Study Cards
Master Cytochrome P450 Polymorphisms with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Flashcard 1: Which antimalarials (4) can cause hemolysis in G6PD?_____, Artesunate, Dapsone, Quinidine
Answer: Primaquine
Flashcard 2: Which gene mutation can confer resistance to ganciclovir, cidofovir, and foscarnet?_____
Answer: UL54
Flashcard 3: Metabolism of warfarin is affected by polymorphisms in the genes for _____ and CYP2C9 (p450 enzyme which metabolizes warfarin)
Answer: vitamin K epoxide reductase complex (VKORC1)
Flashcard 4: _____ is the MC gene responsible for isoniazid resistance
Answer: Kat G
Extra:
Flashcard 5: _____ is a urinary antiseptic that can trigger hemolysis in G6PD deficiency patients.
Answer: Nitrofurantoin
Flashcard 6: Sulfa drugs are contraindicated in _____, as they can precipitate hemolytic anemia
Answer: G6PD deficiency
Flashcard 7: Patient with normal pseudocholinesterase has a dibucaine number of _____
Answer: 80
Flashcard 8: _____ injection, an antisense oligonucleotide, is used in rx of DMD in patients who have a confirmed mutation of the DMD gene that is amenable to exon 45 skipping
