H2 Receptor Antagonists — Flashcards

#1

Drug of choice for prevention of NSAID induced peptic ulcer disease is

#2

Histamine binds to _____ receptors on parietal cells, causing increased H+ secretion

#3

The most effective therapy for NSAID-induced ulcer is _____

#4

The H2 receptor antagonist _____ is a potent inhibitor of cytochrome P-450 and therefore has multiple drug interactions

#5

Side effects of metoclopramide include _____ and depression as a result of central D2 blockade

#6

H2 receptor antagonists are especially effective at reducing _____ secretion of acid, however, they only have modest impact on meal-stimulated secretion of acid

#7

Bile acid resins can lead to _____, which may impair the absorption of fat-soluble vitamins (A, D, E, K)

#8

_____ is CCK-B receptor antagonist used in treatment of gastrinoma/Zollinger-Ellison Syndrome

#9

_____ is a gastroprokinetic agent which acts as a 5-HT4 receptor agonist

#10

_____ (macrolide) can bind GI motilin receptors, increasing GI motility and causing diarrhea

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