Drugs for Inflammatory Bowel Disease — Flashcards

Sulfasalazine is metabolized by _____ into the active component (mesalamine) which is used to treat the colitis aspects of IBD

_____ is approved for treatment of short-bowel syndrome

_____ is made of 5-ASA and an inert compound used in the treatment of Inflammatory Bowel Disease

Treatment of IBD (Crohn's, UC) may involve immunosuppressors, such as _____ and 6-mercaptopurine

Alpha-glucosidase inhibitors (e.g. acarbose, miglitol) are infrequently prescribed due to their ability to cause _____, flatulence, and abdominal pain as side effects

Bile acid resins can lead to _____, which may impair the absorption of fat-soluble vitamins (A, D, E, K)

_____ is CCK-B receptor antagonist used in treatment of gastrinoma/Zollinger-Ellison Syndrome

_____ is a gastroprokinetic agent which acts as a 5-HT4 receptor agonist

_____ (macrolide) can bind GI motilin receptors, increasing GI motility and causing diarrhea

Because PGE1 is involved in physiological responses of the gut mucosa and the uterine smooth muscle, Misoprostol can cause _____ as well as uterine contractions