Topoisomerase Inhibitors — Flashcards

Topoisomerase Inhibitors — Flashcards

Topoisomerase Inhibitors — Flashcards
#1

Anthracyclines (doxorubicin, daunorubicin) treat both _____ malignancies and solid tumors

#2

Antineoplastic agents extracted from the _____ plant is: Vinca alkaloidsalso called Catharanthus roseus

#3

Topotecan, a Topoisomerase I inhibitor, is used to treat cancers of the _____ system and small cell lung cancer

#4

Etoposide and teniposide have activity against both _____ and solid tumor malignancies

#5

Intercalation of Anthracyclines into DNA inhibits the progression of Topoisomerase II and induces eviction of histones

#6

Anthracyclines (doxorubicin, daunorubicin) form _____ which cause breaks in DNA

#7

Antineoplastic agents extracted from the Periwinkle plant is: _____ also called Catharanthus roseus

Flashcard 7 image
#8

_____ is a drug of choice for mesothelioma.

Hint: Antifolate drug

#9

Cetuximab is a monoclonal antibody against the _____ Receptor most commonly used to treat Stage IV colorectal cancer

#10

_____ is a monoclonal antibody against PDGFR- and blocks ligand-mediated receptor activation

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