As an antineoplastic, Methotrexate is primarily indicated for cancers of lymphocytes, particularly _____ and lymphomas
#2
Cerebellar toxicity is seen with which anti-cancer drug?_____
#3
_____ inhibits thymidylate synthase, which catalyzes conversion of dUMP to dTMP (pyrimidine synthesis)
#4
_____ is an antimetabolite that inhibits pyrimidine synthesis inhibiting Ribonucleotide Reductase, thus blocking Thymidine synthesis
#5
Drug of choice for Hairy cell leukemia
#6
_____ is a prodrug of 5-fluorouracil with similar activity
#7
Antineoplastic agents extracted from the Periwinkle plant is: _____
also called Catharanthus roseus
#8
_____ is a drug of choice for mesothelioma.
Hint: Antifolate drug
#9
Cetuximab is a monoclonal antibody against the _____ Receptor most commonly used to treat Stage IV colorectal cancer
#10
_____ is a monoclonal antibody against PDGFR- and blocks ligand-mediated receptor activation
Antimetabolites Indian Medical PG Flashcards - Medical Study Cards
Master Antimetabolites with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Antimetabolites Flashcard Deck - 10 Cards
Flashcard 1: As an antineoplastic, Methotrexate is primarily indicated for cancers of lymphocytes, particularly _____ and lymphomas
Answer: leukemias
Flashcard 2: Cerebellar toxicity is seen with which anti-cancer drug?_____
Answer: Cytarabine
Flashcard 3: _____ inhibits thymidylate synthase, which catalyzes conversion of dUMP to dTMP (pyrimidine synthesis)
Answer: 5-fluorouracil (5-FU)
Flashcard 4: _____ is an antimetabolite that inhibits pyrimidine synthesis inhibiting Ribonucleotide Reductase, thus blocking Thymidine synthesis
Answer: Hydroxyurea
Flashcard 5: Drug of choice for Hairy cell leukemia
Answer: Cladribine
Flashcard 6: _____ is a prodrug of 5-fluorouracil with similar activity
Answer: Capecitabine
Flashcard 7: Antineoplastic agents extracted from the Periwinkle plant is: _____
also called Catharanthus roseus
Answer: Vinca alkaloids
Flashcard 8: _____ is a drug of choice for mesothelioma.
Answer: Pemetrexed
Flashcard 9: Cetuximab is a monoclonal antibody against the _____ Receptor most commonly used to treat Stage IV colorectal cancer
Answer: EGF
Flashcard 10: _____ is a monoclonal antibody against PDGFR- and blocks ligand-mediated receptor activation
Answer: Olaratumab
Keywords: Antimetabolites flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
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