COX-2 Selective Inhibitors — Flashcards

#1

Adverse effects of chronic aspirin use include:- _____ injury- acute interstitial nephritis- GI bleeding

#2

Cyclooxygenase-2 expression is _____ by inflammation

#3

Coadministration of ACE inhibitors with _____ can precipitate acute kidney injury

#4

Aspirin at _____ doses primarily acts by inhibiting cyclooxygenase 1 (COX-1).

#5

What effect may NSAIDs have on K+ levels?_____

#6

_____ and COX-2 are enzymes that produce prostanoids (e.g. prostaglandins)

#7

The effect of intermediate dose aspirin _____ mg/day is antipyretic and analgesic

#8

Acute adverse effects of aspirin use are _____ and tinnitus (CN VIII) (ears ringing).

#9

Sulfasalazine is an anti-_____ therapy primarily indicated for Rheumatoid Arthritis

#10

Chronic gout due to overproduction is treated with _____ or febuxostat, which inhibit xanthine oxidase

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COX-2 Selective Inhibitors Flashcards | Analgesics and Anti-inflammatory Drugs Study Cards - OnCourse