Neuroblastoma — Flashcards

Neuroblastoma — Flashcards

Neuroblastoma — Flashcards
#1

The most common extra-cranial solid neoplasm in children is _____

#2

Good prognosis in neuroblastoma is associated with _____diploidy.

#3

Mutations in MYCN (MIC-2) can cause _____ due to a resultant amplification of the transcription factors activity (nuclear regulator)

#4

Chromosome 1p and 11q losses are associated with a _____ prognosis in neuroblastoma

#5

The most common intra-abdominal neoplasm in children is _____

#6

Neuroblastoma is characterized by increased levels of _____ and vanillylmandelic acid (VMA) in the urine (catecholamine metabolites)

#7

The most common presentation for a _____ is abdominal distention with a firm, irregular mass that can cross the midline

#8

Wilms tumor presents as a large, _____-lateral flank mass and/or hematuria *most common presentation?

#9

Most unilateral Wilms tumors are treated by _____ followed by nephrectomy.

#10

Age younger than _____ years or presentation in adolescence or adulthood is a bad prognostic marker for ALL

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