Molecular Basis of Cancer — Flashcards

Molecular Basis of Cancer — Flashcards

Molecular Basis of Cancer — Flashcards
#1

_____ is the most commonly mutated gene in sporadic breast carcinomas

#2

What is the first cancer to be directly associated with genetic abnormality?_____

#3

Categories of proto-oncogenes include:_____2) Growth factor receptors3) Signal transducers4) Nuclear regulators5) Cell cycle regulators

#4

E-cadherin overexpression is a hallmark of _____ breast carcinoma

#5

What is the mechanism that results in malignancy from the ABL oncogene?_____

#6

Invasive carcinomas become metastatic when they invade the _____ or blood

#7

The following image represents the _____ carcinoma subtype of invasive ductal carcinoma (breast): hint: the circled area is lymphatics

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#8

In HPV-_____ SCC of the oral cavity, patients generally present with large primary lesions with variable nodal disease.

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#9

What type of rhabdomyosarcoma is shown in the given image? _____ **most common subtype

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#10

TNM classification of laryngeal carcinoma: No answer _____

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